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Description

321 Ligandreceptor binding results in the release of the Notch intracellular domain (NICD) and NICD interaction with recombination signal-binding protein immunoglobulin kappa J (RBPJ) to initiate the transcription of downstream target genes such as HES/HEY

Laryngoscope 111, 528534

KD, n = 9

the increase in oxygen radicals due to a lack of reduced glutathione can be optimally intercepted, which destroy the molecular and cell structure and can thus cause malignant degeneration or cell death