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Children with IBD generally have insufficient fiber intake, and supplementation with fiber and probiotics can restore symbiotic bacteria abundance, enhance barrier function, and reduce inflammation [250, 251], Moreover, IL-10 knockout mice fed a low-fiber diet show mucosal layer degeneration and severe colitis, directly confirming that genetic background amplifies the dietary effects [252]

Finally, direct evidence was provided also by Bassareo et al

or (ii) The amount determined under the fee schedule as described in paragraph (o)(3) of this section

Impaired calcium signaling in astrocytes modulates autism spectrum disorder-like behaviors in mice