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287 Recent studies have shown that in obese individuals, increased fat is associated with iron homeostatic imbalance manifested as elevated ferritin, elevated serum hepcidin, and increased risk of iron overload

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A significant advantage of the S , S -tetrazine staple is the ability to introduce probes exploiting inverse electron demand DielsAlder reactions, which make tetrazine staples hold the promise of dual roles: confining peptide conformation and introducing photophysical or other potential probes (Figure 6D) [128]

1h), so we continued with the MM + WntS + TRULI combination, hereafter termed h-HepOrg expansion medium 1 (EM1)