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We used the Grading of Recommendations, Assessment, Development and Evaluation approach to determine the certainty of evidence for each outcome and strength of recommendations

Following the closure of the factory, BAT plans to sell the land on which it is located via a public tender exercise that is expected to be completed around May subject to shareholders approval

Canadian Border Services Agency (CBSA) and Health Canada may seize parcels if the products have not been specifically approved for the Canadian market

Smoking rates have fallen in recent years but vaping rates have risen sharply, especially among under-35s and those who have never used cigarettes