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Hrovatin et al., 2023

You can apply a numbing agent 30 minutes prior to the treatment if you are particularly sensitive to pain

Recently, ultradeformable liposomes (UL) have been developed by scientific researchers, which greatly increased the skin permeation ability of rosmarinic acid by UL containing oleic acid, exhibiting potential as a formulation for development for external use (Subongkot et al., 2021)