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146 These fatty acids are also metabolized into compounds called resolvins that protect nerves from inflammatory damage

Curculigoside has been reported to downregulate Beclin-1 expression and the LC3-II/I ratio, potentially reducing autophagy-related damage (Meng et al., 2024)

Deeper scientific understanding of PD would lead to better preclinical detection and prophylaxis, validation of biomarkers, confirmation of genetic and environmental risk factors, and more prolonged symptom control with fewer adverse effects