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Researchsupported contexts Cystic Fibrosis Chronic otitis media with effusion HIVpositive individuals Idiopathic Pulmonary Fibrosis Chronic rhinitis Chronic smoking* and emphysema* *Both have been linked with lower glutathione levels in the epithelial lining fluid

Competing interests A.GH is a member of the editorial board of BMC Endocrine Disorders

Same results were obtained on culture models, the P e values of ibuprofen were 0.28 and 0.53 10 6 cm/s across a porcine brain endothelial cell line and a rat primary brain endothelial based BBB models, respectively [71]

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