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Thus, the invention provides a compound of formula (I), its stereoisomers and/or its pharmaceutically acceptable salts or a pharmaceutical composition comprising the compound, its stereoisomers and/or its pharmaceutically acceptable salts for use as a medicament

[7] [9] Caution is advised in individuals with renal insufficiency or those on dialysis, as impaired clearance may increase the risk of accumulation and toxicity

Begin CLA at a lower fraction of the commonly studied dose and gradually increase toward 3.2 grams per day if metabolic markers remain stable

PubMed CentralPMCID: PMC2798902 Thompson CA, Mauck K, Havyer R, et al