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Its well-tolerated by virtually all patients, with no significant side-effects reported in the research literature

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Although it is currently not clear if tamoxifen is effective in targeting other types of drug resistant cells that over-express P-gp, based on our current understanding of the mechanism of collateral sensitivity of P-gp-overexpressing cells, we speculate that tamoxifen alone or in combination with rotenone could reduce the rise of drug resistant tumor cells