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While the use of trastuzumab with chemotherapy in the neoadjuvant setting is associated with higher complete response rates, its impact on disease-free survival and overall survival remains unclear when compared to adjuvant treatment 54

Taken in combination, MPH could induce apoptosis and neurodegeneration through its action on the CREB signalling pathway and oxidative stress generation through RAC1 and CAMK4

pylori and its OMVs modulate ferroptosis through three primary mechanisms: i) Reducing cellular iron uptake and lipid peroxide production by downregulating transferrin receptor/transferrin receptor protein 1 (TFRC/TFR1) and the endosomal metal reductase six-transmembrane epithelial antigen of the prostate 3