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Physical activity and exercise are most effective for MASLD patients when a personalized and tailored approach is used, making RE essential for maintaining lean mass and reducing frailty in sarcopenic or older MASLD patients

One is that GSSG and GS-X produced in cardiomyocytes are pumped out by multidrug resistance protein 1 (MRP1), preventing GSSG or GS-X accumulation in cardiomyocytes [33, 34], and subsequently enter the -glutamyl cycle