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10.1016/j.jhep.2017.05.007 161 WitkowskiM.WeeksT

425,426,427 These innovative medicines delve deeper into AD mechanisms and present diverse target choices, holding the potential to halt or reverse AD progression

Together, both works demonstrate that CYP2D6 and CYP2C19 polymorphisms significantly influence antidepressant plasma exposure, which directly affects pharmacodynamic mechanisms underlying efficacy and side-effect profiles