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Five amino acids in three HLA proteins explain most of the association between MHC and seropositive rheumatoid arthritis

Enzymes like acyl-CoA synthetase long-chain family member 4 (ACSL4) and lysophosphatidylcholine acyltransferase 3 (LPCAT3) are central to incorporating PUFAs into membranes, sensitizing cells to ferroptosis (7173)

In conclusion, our findings indicate that the trafficking of GNPT within the cell relies on multiple coordinated mechanisms

coli revealed that at least some loss of ATP upon HOCl stress is due to conversion of cellular ATP to inorganic polyphosphates (polyP), which by themselves can act like ATP-independent chaperone holdases, effective in stabilizing unfolding proteins and preventing protein aggregation both in vivo and in vitro [282, 283] (Fig