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A search on clinicaltrials.gov for relevant unpublished trials revealed that NCT00086684, sponsored by Johnson & Johnson, was terminated early for lack of efficacy

6.3-1 N, Stephen Provencher Inc., Oakville, Ontario, Canada), using a basis-set of simulated model spectra for the specific 7 T sSPECIAL sequence

This blockage can especially impact speech and cognitive development

Because accurate determination of the NADPH consumption rate can be confounded by the reduction rate of NADP + , we inhibited key biochemical pathways that reduce NADP + back to NADPH in LPS-stimulated Ms, including glucose-6-phosphate dehydrogenase (G6PD), isocitrate dehydrogenases and folate-mediated one carbon metabolism that can contribute to the reduction of NADP + [1820]