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In particular, we have ascertained that ROS generation induced by LA triggers the activation of the EGFR/ERK/AP1 transduction pathway, leading to the upregulation of p21 Cip/WAF1 in a p53-independent manner

The activity of soil microbes and water penetration through cracks in the coating allow the urea to escape into the soil

Laudenbach DE, Ehrhardt D, Green L, Grossman A (1991) Isolation and characterization of a sulfur-regulated gene encoding a periplasmically localized protein with sequence similarity to rhodanese

65,66 While little is known about 8-THC specifically, it is a mixed agonist of CB1 and CB2 but has less affinity for CB1 than 9-THC, potentially explaining why its euphoric effects are milder