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Description

This cascade leads to a significant increase in TFR1 and Fe 2+ levels, promoting neuronal ferroptosis and lipid peroxidation, which exacerbates muscle atrophy and motor dysfunction in mice

In contrast to M1, M2 mechanisms incorporate location-related, mutually connected, and cascade-like reactions

Light-sensitive nanoparticles and ASCT2 inhibitors have been investigated for the treatment of breast cancer [79], and their applications in DSMTs should be explored in future studies