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Description

Cell Res (2002) 12(56):31120

The rationale for combining them is mechanistic complementarity (different signaling pathways, both implicated in tissue repair) and clinical anecdote in the peptide-therapy community not formal head-to-head or combination-vs-monotherapy data

ROS concurrently trigger intracellular signaling networks, including the NFB pathway, thereby enhancing matrix metalloproteinase (MMP) expression and accelerating degradation of the cartilage matrix