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These molecules can be naturally occurring in the body or synthesized in a laboratory

In clinical trials, ALA has been tested in combination with other antioxidants such as vitamins C and E and polyunsaturated fatty acids in conjunction with NB-UVB phototherapy

It is worth noting that febuxostat inhibits ABCG2 more strongly than the two known ABCG2 inhibitors (Ko143 and elacrida), which means that febuxostat has not only advantages over these two inhibitors but also stronger in safety and ability than other ABCG2 inhibitor ( Xanthine Oxidase Inhibitors Allopurinol Allopurinol, a xanthine oxidase inhibitor, is one of first-line drugs for the management of gout (Stamp et al., 2016

Prodrugs include acid derivatives such as, for example, esters prepared by reaction of the parent acid with a suitable alcohol, or amides prepared by reaction of the parent acid compound with a substituted or unsubstituted amine, or acid anhydrides, or mixed anhydrides