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The rationale for butyrate enemas in radiation proctitis is the same as for diversion colitis: radiation destroys the mucosal microenvironment, depletes butyrate-producing bacteria, impairs colonocyte energy metabolism, and compromises the barrier

They both efficiently and rapidly catalyze the reversible conversion of BCAAs and BCKAs

AGEs, recognized as uremic toxins in DN, are implicated in various pathways contributing to cellular senescence

Isoproterenol hydrochloride, which has physiological effects similar to those of the stimulating hormone epinephrine, is a powerful cardiac drug that could seriously harm or prove fatal if given by accident to a patient with an underlying heart condition