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Description

doi:10.4103/jpp.JPP_173_16

Local and systemic effects of cigarette smoking on folate and vitamin B-12

Koppe T, Patchen B, Cheng A, Bhasin M, Vulpe C, Schwartz RE, Moreno-navarrete JM, Fernandez-real JM, Pissios P, Fraenkel PG (2017) Nicotinamide N -methyltransferase expression decreases in iron overload, exacerbating toxicity in mouse hepatocytes

As mentioned previously, the widespread and prolonged use of histamine H 2 -receptor blockers and proton pump inhibitors for ulcer disease also may cause impaired breakdown of vitamin B 12 from food, causing malabsorption and eventual depletion of B 12 stores