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Oscarson et al

IFNs bind to cell surface receptors that are associated with janus kinases (JAK), which then phosphorylate intracellular receptor chains, generating docking sites for the signal transducer and activator of transcription (STAT

FADH 2 -dependent halogenases are primarily involved in the electrophilic halogenation of tryptophan, phenol and pyrrole moieties of secondary metabolites (van Pe and Patallo, 2006) (Figure 2)