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Nat Rev Endocrinol 21 , 769782 (2025)

The amount of DA released from primary cultured dopaminergic neurons exposed to high-KCl concentrations was normalised with the DA content in a low-KCl buffer

Owing to the same mechanism and effectiveness as iVNS, taVNS is simpler, more portable, and safer, which gives it the potential advantage of easier translation to clinical use in a wide range of applications (Ben-Menachem et al., 2015)