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FcRn binding to HA-Fc fusions in ELISA 96-well EIA/RIA plates (Corning) were coated with a recombinant human albumin variant (8 g/mL in PBS/ 100 L per well) engineered to bind pH independently to human FcRn 29

Figure 2 shows that 48 hours treatment with the mentioned drug concentrations resulted in a statistically substantial drop in GPx activity at 7 and 14 M doses compared with control groups

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