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To solve the above problem, the high H 2 O 2 concentration in the tumor region has been used to catalyze the in situ generation of oxygen

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Macrolides Apart from their antimicrobial activity, macrolides have been increasingly used in clinical practice for the treatment of a variety of chronic pulmonary diseases because of their anti-inflammatory and immune-modulatory properties.2932 Although solid evidence to justify long-term macrolide therapy in many of these disorders is still lacking, beneficial effects have been found in small clinical trials of patients with non-CF BE.3339 There were considerable variations in the study design of many of these trials, including duration, dose and macrolides tested and outcome measures evaluated but most of them showed consistent evidence of a decrease in sputum volume and some reported a decrease in exacerbation frequency