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doi:10.1053/j.ajkd.2021.02.328

Tran, MD uses comprehensive blood tests to determine the severity of the deficiency, measuring B12 levels, methylmalonic acid, and homocysteine

This is not a conservative recommendation

"The Real Housewives of New Jersey get to be super skinny while the real school kids of New Jersey get to get diabetes at the age of 12." Hari's most optimistic scenario: that the drugs do turn out to be highly effective with little risk and are accessible to all