glutathione switch persister cells Sublethal cytochrome c release generates drug-tolerant cells: Cell How pancreatic cancer survives ferroptosis?
How pancreatic cancer survives ferroptosis? Pancreatic ductal adenocarcinoma (PDAC) tumors harboring KRAS mutations exhibit relative resistance to iron dependent form of cell death, ferroptosis, compared with other tumor types but the mechanisms remain Low GPX4 drives a sustained drug tolerant persister state in TNBC by a targetable adaptive FSP1 upregulation ScienceDirect Additional data demonstrating that persister cells have a disabled Download Scientific Diagram Frontiers Drug tolerant persister cells: the deadly survivors in hematological malignancies
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