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A key concept for understanding this interface is the model of allostasis (adaptation) and allostatic load (pathophysiology) [6] that we review below examining this model in relation to new insights from the recent work on the link between mitochondrial metabolism and epigenetic function to promote healthy behaviors and cognitive function

Neonatos: inicial, 50 mg/kg/da divididas en dosis cada 3-4 h, ajustando, en funcin de la necesidad a 50-100 mg/kg/da en dosis divididas cada 3-4 h (en casos graves, 300 mg/kg/da)

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The guideline identifies specific populations in which dietary supplementation may be necessary, such as women who are pregnant or lactating and adults older than 50