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Regarding the systemic toxicity of the treatments, we observed no unusual changes in the body weight of the mice during the observation period and no significant differences in the body weight at the end of the observations, right before sacrificing them (Supplementary Fig

Toru Nyunoya (Lovelace Respiratory Research Institute, USA) [22] and Dr

Both hydrophilic and hydrophobic fractions underwent capillary electrophoresis-mass spectrometry (CE-MS) and liquid chromatographymass spectrometry (LCMS), respectively