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however, emerging evidence has revealed that it can also suppress autophagy initiation under specific metabolic conditions

Molecular dynamics simulations of CRM1 complexes The three-dimensional structure of CRM1 was obtained from the Protein Data Bank using entry 6X2M, which was crystallized in complex with GTP-binding nuclear protein Ran and Ran-specific GTPase-activating protein 1, at a resolution of 2.35 [28]