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Description

10.3760/cma.j.cn112139-20240218-00072 96 WangD.LuK.ZouG.WuD.ChengY.SunY

1 Data shown for timepoints when sample size n was 30% of total sample size (N) in a given dosing regimen group

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Considering that heme oxygenase-1 (HO-1) gene KO and treatment with zinc protoporphyrin IX (a HO-1 inhibitor) reduced Fe + levels and ROS-mediated LPO in PR cells, it has been proposed that HO-1 is a critical modulator of PR ferroptosis induced by atRAL (108)