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A possibility is the suppression of growth factor receptor signaling or the inhibition of Raf by AMPK

doi: 10.1016/j.tem.2019.02.006 Summary Keywords macrophages, reactive oxygen species (ROS), mitochondria, innate immunity, redox signaling, inflammasome, monoamine oxidase, protein oxidation Citation Canton M, Snchez-Rodrguez R, Spera I, Venegas FC, Favia M, Viola A and Castegna A (2021) Reactive Oxygen Species in Macrophages: Sources and Targets

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In male models, exogenous HCG stimulates Leydig cell testosterone production and Sertoli cellmediated spermatogenesis, making it a key tool in hypogonadotropic hypogonadism and testicular function studies