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doi: 10.1093/toxsci/kfq175

These results support the proposal that frataxin is the iron donor for ISC assembly

Across the studies considered in this section, a consistent theme is that polyphenolexercise combinations tend to rebalance the Bax/Bcl2 axis away from indiscriminate cell loss in normal tissues and toward more selective, contextappropriate apoptosis, although the strength of this conclusion varies by model and outcome