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In the ER up to 20 different oxidoreductases, for example the peroxiredoxin Prx4 or the glutathione peroxidase-like enzymes Gpx7 and Gpx8 are found besides PDI and for at least some of them it has been proposed that they possibly oxidize PDI (Nguyen et al., 2011

Glutathione is the main mediator of detoxification reactions, by which toxins, both those produced by our body and those from outside, are eliminated A lack of glutathione, on the other hand, is associated with oxidative stress , a set of alterations that are among the main enemies of the health of cells and tissues, since they play a central role in their aging and in some cases can lead to real diseases

By doing so, it helps reduce the risk of cancer

Iodine deficiency compromises thyroid hormone production and leads to serious diseases including irreversible cretinism, pregnancy complications, goiter, and decreased cognitive function