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Parenteral administration of minute amounts of endotoxins to humans elicits an inflammatory reaction typical of SIRS (fever or hypothermia, tachycardia, hyperpnea, leukocytosis, and hypotension), whereas larger amounts of administered endotoxins typically produce sepsis and shock [66, 67]

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[145] showed that microwave-synthesised CQDs significantly reduced HEWL amyloidogenesis by delaying nucleation, inhibiting b-sheet conversion, and disrupting protofibril elongation, ultimately yielding fewer and shorter aggregates with reduced cytotoxicity [145]