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Tightness in the throat and chest can occur with B12 deficiency and it is commonly mislabelled as anxiety. The mechanism is neurological and autonomic, not psychological. Here is the clear biology you Vitamin B12 Injections for Aging and Longevity InVita Wellness Vitamin B12 and Nerves Parasympathetic and Sympathetic Nervous System Dysfunction and Monitoring Springer Nature Link
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