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In another follow-up study, VitE (50 mg/d) was administered for 58 years to older male smokers (5069 years old), which revealed that VitE administration reduced the incidence of pneumonia in older men in different subgroups (99)

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These include variability in dosing, reported adult dosages range from 30 to 300 mg/day, depending on the clinical indication, formulation, and treatment duration, and the lack of standardized dosing regimens, which complicates cross-study comparisons ( In the near-term, PYC is most likely to serve as an adjunctive or nutraceutical support rather than a standalone therapeutic agent

An analysis of national pneumococcal vaccination data in Korea revealed that previous pneumococcal vaccination in the older population effectively improved hospitalization rates and 30-day mortality among patients hospitalized for pneumonia (121)