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Strategies to minimize reactions include rotating injection sites consistently to avoid repeated trauma to the same area, ensuring the solution is at room temperature before injection (cold injections can increase irritation), injecting slowly rather than quickly, and using a smaller gauge needle for less tissue trauma

Upon examination, it was reported that the corticosteroid appeared to significantly worsen the muscle damage in the murine models

When applied topically, it improved wound contraction, formation of new tissue, and stimulated new blood vessel growth

This allows systemic distribution to tissues throughout your body rather than limiting effects to the application site