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Special populations Certain groups should exercise caution when taking vitamin B12 supplements: Pregnant and breastfeeding women : Vitamin B12 is required during pregnancy and breastfeeding to prevent cognitive and developmental delays, but taking only the recommended amounts is essential

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Numbness during Mounjaro treatment is typically caused by pre-existing diabetic neuropathy, rapid improvements in blood glucose control, nutritional deficiencies (especially vitamin B12), or concurrent medications rather than the tirzepatide itself