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*NAC supplementation is not used to treat or prevent medical conditions

DSIP is found in both free and protein-bound forms in the hypothalamus, limbic system, and pituitary gland, as well as in peripheral organs including the gut secretory cells, pancreas (where it co-localises with glucagon), and plasma with brain and plasma DSIP concentrations showing a marked diurnal variation that correlates with circadian rhythm in humans, with levels lowest in the morning and higher in the afternoon

Given the metabolic reliance of retinal ganglion cells on glia as highlighted above, it is likely that the shift in glial phenotypes away from supportive roles and towards pro-inflammatory phenotypes will lessen their ability to support retinal ganglion cells

Detox and antioxidant blends are useful when a broader formula is preferred, but they should still be checked carefully for overlap and suitability