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The vapor pressure is the minimum pressure required to keep water in its liquid form

Mehak Gulzar: Writing- Original draft preparation, Investigation, Methodology

Nutrients 7 (4), 28392849

1 Introduction Diabetic nephropathy (DN) is a severe microvascular complication of diabetes mellitus, affecting an estimated 30%40% of diabetic patients and serving as the leading cause of end-stage renal disease (ESRD) globally ( Ferroptosis is an iron-dependent form of regulated cell death driven by lipid peroxidation and characterized by the accumulation of iron and reactive oxygen species ( Acteoside (ACT), a natural phenylpropanoid glycoside abundant in Rehmannia glutinosa and other medicinal herbs, possesses potent antioxidant, anti-inflammatory, and antifibrotic properties ( in vivo studies have demonstrated that ACT ameliorates renal interstitial fibrosis and improves kidney function in streptozotocin-induced DN models, reducing serum creatinine and blood urea nitrogen levels while attenuating histopathological damage ( Network pharmacology enables systematic mapping of bioactive compounds, targets, and signaling pathways, shedding light on the mechanisms by which traditional Chinese medicines act in complex disorders ( in silico pharmacology predictions, we conducted in vivo experiments in STZ-induced DN mice