Mal-Acetyl-Beta-Ala-Val-Cit-PAB(m-PEG8)-MMAE exatecan The covalent linkage between the

The covalent linkage between the HaloTag ligand and HaloTag protein enables rapid isolation and purification

hydroxyethoxy)

291 SMILES BrCCCCCCC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

2-d3)acetamido]benzoate Synonyms methyl 4-[(2

Mal-Acetyl-Beta-Ala-Val-Cit-PAB(m-PEG8)-MMAE exatecan The covalent linkage between theSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate