TMP-POM 7c cyclopropene 313 SMILES OCCCC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC)
TMP-POM 7c cyclopropene 313 SMILES OCCCC1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC)The TMP tag is based on the tight binding between trimethoprim (TMP), a synthetic antibiotic, and Escherichia coli dihydrofolate reductase (eDHFR), a small enzyme with a high affinity for TMP. By fusing eDHFR to a protein of interest and introducing TMP linked to a probesuch as a fluorescent dye, biotin, or other functional groupresearchers can selectively label and study proteins in their native cellular environment. TMP POM 7c is a trimethoprim
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