4-{4-[(tert-butoxy)carbonyl]piperazin-1-yl}butanoic acid amine A novel cereblon modulator recruits

A novel cereblon modulator recruits GSPT1 to the CRL4CRBN ubiquitin ligase

39 SMILES Cl

catalyzed click reaction

378 SMILES C[C@H](NC1=CC=C2C3=NC(=CN3CCOC2=C1)N1[C@@H](COC1=O)C(F)F)C(N)=O Purity (HPLC) >= 95% Physical Appearance White solid Solubility DMSO

4-{4-[(tert-butoxy)carbonyl]piperazin-1-yl}butanoic acid amine A novel cereblon modulator recruitsNitrogen Heterocycle Based Linker (NHBL). Binfunctional amine carboxylic acid linker. Product Name 4 {4 [(tert butoxy)carbonyl]piperazin 1 yl}butanoic acid Synonyms CAS Number 1240619 81 1 Related CAS Molecular Formula C13H24N2O4 Molecular Weight 272. 345 SMILES CC(C)(C)OC(=O)N1CCN(CCCC(O)=O)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement