Mal-Propionyl-Beta-Ala-Val-Cit-PAB(m-PEG8)-PNP Thalidomide 562 SMILES: OC1=CC2=C(C=C1)C1(OC(=O)C3=CC(=CC=C13)C(=O)NCCOCCOCCOCCN=[N]#N)C1=CC=C(O)C=C1O2

562 SMILES: OC1=CC2=C(C=C1)C1(OC(=O)C3=CC(=CC=C13)C(=O)NCCOCCOCCOCCN=[N]#N)C1=CC=C(O)C=C1O2

265 Purity (HPLC) >= 95% Solubility DMSO

Product Name: Thalidomide-O-C5-amine Synonyms: 1H-

Product Name Lenalidomide-5'-CO-PEG4-C2-amine HCl Synonyms CAS Number n/a Related CAS 2727154-04-1 (free base) Molecular Formula C24H35ClN4O8 Molecular Weight 543

Mal-Propionyl-Beta-Ala-Val-Cit-PAB(m-PEG8)-PNP Thalidomide 562 SMILES: OC1=CC2=C(C=C1)C1(OC(=O)C3=CC(=CC=C13)C(=O)NCCOCCOCCOCCN=[N]#N)C1=CC=C(O)C=C1O2SOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an activating leaving group, enabling efficient and selective conjugation of the payload to the linker. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as