Azide-Propionyl-Val-Cit-PAB(m-PEG8)-Exatecan Size:5mg Product Name CA-amide-PEG3-Biotin Synonyms biotin

Product Name CA-amide-PEG3-Biotin Synonyms biotin Halotag Ligand PEG3 CAS Number N/A Related CAS N/A Molecular Formula C29H53ClN4O8S Molecular Weight 653

Product Name HQ461 Synonyms CAS Number 1226443-41-9 Related CAS Molecular Formula C15H15N5OS2 Molecular Weight 345

65 SMILES [2H]C([2H])([2H])N(C1=C(F)C=CC=C1Cl)C([2H])([2H])[2H] Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

BI-3802 has antitumor activity

Azide-Propionyl-Val-Cit-PAB(m-PEG8)-Exatecan Size:5mg Product Name CA-amide-PEG3-Biotin Synonyms biotinSOLU KNEX cleavable linker features a Val Cit dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC