Mal-Propionyl-PEG4-Val-Cit-PAB(m-PEG4) Size:50mg Designed for ADC research

Designed for ADC research

NCCC#CC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

692 Purity (HPLC) >= 95% Solubility DMSO

Product Name DOTA-tris(t-Bu)ester-C2-propanamido-maleimide Synonyms CAS Number Related CAS Molecular Formula C37H63N7O10 Molecular Weight 765

Mal-Propionyl-PEG4-Val-Cit-PAB(m-PEG4) Size:50mg Designed for ADC researchSOLU KNEX cleavable linker features a Val Cit dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG4 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker architectures, SOLU KNEX