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doi: 10.1016/j.jns.2016.05.056

Generation of pluripotent stem cells from eggs of aging mice

The temporal dynamics of GCLC loss relative to clinical symptom onset are also unclear and warrant longitudinal investigation

Deeper scientific understanding of PD would lead to better preclinical detection and prophylaxis, validation of biomarkers, confirmation of genetic and environmental risk factors, and more prolonged symptom control with fewer adverse effects