DBCO-Lys(m-PEG4)-Val-Cit-PAB(m-PEG8) Thalidomide Product Name NDB-TM Synonyms CAS

Product Name NDB-TM Synonyms CAS Number 871510-38-2 Related CAS Molecular Formula C10H10N4O3S Molecular Weight 266

802 Purity (HPLC) >= 95% Solubility DMSO

39 Purity (HPLC) >= 95% Solubility DMSO

64 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCCCCCBr)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

DBCO-Lys(m-PEG4)-Val-Cit-PAB(m-PEG8) Thalidomide Product Name NDB-TM Synonyms CASSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a DBCO Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further