DBCO-Propionyl-Val-Cit-PAB(m-PEG8)-PNP sir S)-AHPC-CO-C10-NH2 HCl Synonyms CAS Number

S)-AHPC-CO-C10-NH2 HCl Synonyms CAS Number 2341796-75-4 Related CAS 2341796-74-3 (free base) Molecular Formula C33H53Cl2N5O4S Molecular Weight 686

It features a disulfide bond

emission maximum = 525 nm

Indisulam promotes the recruitment of RBM39 (RNA binding motif protein 39) to the CUL4-DCAF15 E3 ubiquitin ligase

DBCO-Propionyl-Val-Cit-PAB(m-PEG8)-PNP sir S)-AHPC-CO-C10-NH2 HCl Synonyms CAS NumberSOLU KNEX cleavable linker features a Val Cit dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The PNP (para nitrophenyl) moiety serves as an activating leaving group, enabling efficient and selective conjugation of the payload to the linker. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine