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167,168,169 Unlike other nucleic acid-based drugs, aptamers specifically recognize and bind target molecules, such as peptides, proteins, viruses, bacteria, and cells, relying on their unique three-dimensional conformation

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Additionally, the development of pharmacological agents that precisely modulate intracellular iron homeostasis, such as iron chelators or iron oxide NPs, or enhance iron bioavailability specifically within the TME, may facilitate the targeted exploitation of ferroptosis pathways

Use of a Hybrid Adeno-Associated Viral Vector Transposon System to Deliver the Insulin Gene to Diabetic NOD Mice